Cheesy Southwest Chicken Lasagna Roll Ups RecipeLasagna noodles are rolled around a filling of chicken, beans, and bell pepper and topped with a cheesy, aromatic sauce. These lasagna roll-ups are a delicious twist of an Italian favorite with the zesty essence of Southwestern flavors!

Two southwest lasagna roll ups on a white plate.

Why We Love This Southwest Lasagna Recipe

I know just how difficult it can be to come up with new and delicious dinner ideas that your family is guaranteed to love. This cheesy Southwest lasagna is a bold, Tex-Mex take on classic lasagna that the whole family will love!

This festive combination is bold and comforting. The filling is made of chicken, beans, bell peppers, green onions, cheese, and taco seasoning, while the sauce is a mixture of cream cheese and red enchilada sauce for a bold yet creamy flavor!

Cheesy Southwest Chicken Lasagna Rolls are easy to make, especially if you use leftover chicken or shredded rotisserie chicken! Throw in whatever beans and veggies you have on hand, and cover it with some more cheese and you will have a seriously amazing dinner in no time.

Spatula taking a lasagna roll up from a blue baking dish.

Ingredients You Need

  • Dried Lasagna NoodlesOne box will fit a 9×13 baking tray
  • Old El Paso Red Enchilada Sauce This gives it a southwest flavor
  • Cream Cheese To make the sauce thick and creamy
  • Chopped Cooked Chicken This is great for using up leftover chicken, also try rotisserie chicken!
  • Black Beans Make sure that they are drained well
  • Chopped Bell Pepper – I like to use two different colored peppers
  • Garlic ClovesFinely minced
  • Shredded Mexican Blend CheeseThis will be divided between the filling and the topping, feel free to use mozzarella cheese if that is what you have on hand
  • Chopped Scallions – Adds in a nice zesty crunch and some coloring
  • Old El Paso Taco Seasoning Packet – Brings in the Tex Mex flavoring

How To Make Southwest Lasagna Roll Ups

Cheesy Southwest Chicken Lasagna Rolls are simple to make in just a few easy steps!

  1. Start by cooking lasagna noodles to al dente. Drain them well and lay them out on a clean tea towel.
  2. Puree the red enchilada sauce with cream cheese. The enchilada sauce blends perfectly with the cream cheese, giving it a perky taste.
  3. Mix black beans, cooked chicken, peppers, scallions, cheese, and Old El Paso Taco Seasoning together. Roll the mixture into the lasagna noodles.
  4. Then pour the sauce over the top and bake!

As the Cheesy Southwest Chicken Lasagna Rolls bake, the cheese sauce works its way into the rolls to make them extra rich and saucy! Because of the cheese and prepared enchilada sauce in this recipe, there is no need to add any extra salt.

Pro Tip: If the cheese is starting to get too toasty on the top, cover the baking dish with foil!

Get the Complete Southwest Chicken Lasagna Roll Ups Recipe + VIDEO Below. Enjoy!

Serving Suggestions

Easy lasagna roll ups can be served on their own or with a variety of side dishes!

Serve this cozy dish with Classic Garlic Bread, Mexican Street Corn Salad, Brazilian Chopped Salad, or Crunchy Beet and Carrot Slaw

You can also serve these lasagna enchiladas with refried beans with homemade queso and salsa!

Southwest lasagna rolls in a baking dish after being baked.

Frequently Asked Questions

Can this be made the day before and put in the fridge?

Absolutely! You can prep these cheesy Southwestern lasagna rolls ups all the way up to baking, then cover and refrigerate for several days. Straight from the refrigerator, the baking time will be closer to 40-45 minutes.

How long can leftovers last in the fridge?

When they are stored in an airtight container, these rolls can last 3 to 5 days in the fridge.

Do the leftovers freeze well?

Yes, this is a great freezer recipe. Cover well and freeze for up to 3 months. Place it in the fridge the night before you want to serve it, then bake it in the oven to reheat. 

Is this dish spicy?

The spice in this dish comes from the red enchilada sauce and the taco seasoning, neither of which is that spicy. If you like a spicy kick, add some cayenne pepper or red pepper flakes to the filling!

Spatula serving a lasagna roll up.

Can I use a different protein?

Yes! Try adding shredded pork or ground beef to this recipe for a similar texture. You can also add pre-cooked ground beef or ground turkey but this will add a bit of moisture so the lasagna will be saucier!

Can I add extra vegetables?

Sure! Consider mixing in chopped zucchini, kale, or spinach.

Can you boil oven-ready lasagna noodles for roll ups?

Yes, in order to get the oven-ready noodles soft enough to roll up, you can boil them until al dente!

Can I make these lasagna roll ups vegetarian?

Absolutely! You can simply omit the chicken and add extra beans for vegetarian southwest lasagna rolls, or add in some diced tofu for some extra protein!

Other Great Dinner Recipes

Disclosure: This post is sponsored by Ole El Paso. All opinions are my own.

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Southwest Chicken Lasagna Roll Ups Recipe

Prep Time: 20 minutes
Cook Time: 40 minutes
Total Time: 1 hour
Cheesy Southwest Chicken Lasagna Rolls Recipe – Lasagna noodles are rolled around a filling of chicken, beans and bell pepper and topped with a cheesy, aromatic sauce. These lasagna roll ups are a delicious twist of an Italian favorite with the zesty essence of Southwestern flavors!
Servings: 12 rolls



  • Preheat the oven to 350 degrees F. Coat a 9 x 13 inch baking dish with nonstick cooking spray. Set a large pot of salted water over high heat, and bring to a boil.
  • Once boiling, cook the lasagna noodles according to the package instructions. Once cooked to al dente, lay them out on a clean tea towel.
  • Meanwhile, place the Old El Paso Red Enchilada Sauce in the blender and add the cream cheese. Blend until smooth. Pour half of the cheese sauce into the baking dish.
  • In a large bowl, mix the cooked chicken, black beans, bell peppers, garlic, 2 cups shredded cheese, scallions, and taco seasoning. Spread the mixture evenly over 12 lasagna noodles. Roll each noodle, tucking bits back into the rolls if they fall out. Place the rolls in the baking dish. Once all the rolls are in the dish, pour the remaining sauce over the top.
  • Bake for 30-35 minutes, then sprinkle the remaining cheese over the top. Garnish with chopped scallions or cilantro if desired.



Store in an airtight container in the refrigerator for up to 3-5 days!


Serving: 1roll, Calories: 389kcal, Carbohydrates: 42g, Protein: 18g, Fat: 16g, Saturated Fat: 8g, Cholesterol: 53mg, Sodium: 632mg, Potassium: 320mg, Fiber: 5g, Sugar: 5g, Vitamin A: 1165IU, Vitamin C: 17.9mg, Calcium: 196mg, Iron: 2mg
Course: Main Course
Cuisine: Tex-Mex
Author: Sommer Collier
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